|
Symbol Name ID |
Adar
adenosine deaminase, RNA-specific MGI:1889575 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating antibody level |
Lymphocytosis |
Chronic lymphatic leukemia |
Generalized lymphadenopathy |
Splenomegaly |
Hepatosplenomegaly |
Hepatitis |
Increased circulating interferon-gamma concentration |
Increased circulating Interferon-alpha concentration |
Chilblains |
Atopic dermatitis |
Skin rash |
Myositis |
Panniculitis |
Pneumonia |
Autoimmunity |
Antiphospholipid antibody positivity |
Recurrent lower respiratory tract infections |
| Disease(s) Associated with ADAR | ||||||||||||||||||
| Aicardi-Goutieres syndrome |
| Mouse Phenotypes | immune system phenotype |
abnormal spleen morphology |
increased circulating interferon-alpha level |
abnormal circulating interferon-beta level |
increased circulating interleukin-1 level |
increased circulating interleukin-17 level |
increased circulating interleukin-6 level |
abnormal chemokine level |
increased CXCL10 level |
increased susceptibility to Orthomyxoviridae infection |
increased susceptibility to Paramyxoviridae infection |
|
| Availability | Mouse Genotype | |||||||||||
| Adarem2Qwan/Adarem2Qwan | * | |||||||||||
| Adarem3Qwan/Adarem3Qwan | * | |||||||||||
| Adartm1Olds/Adartm1Olds | ||||||||||||
| Adartm2Phs/Adartm2Phs | ||||||||||||
| Adarem1Stsn/Adartm1Olds | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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